The hepatobiliary disease is a broad term that refers to a variety of liver and biliary system diseases caused by viral, bacterial, and parasite infections, neoplasia, toxic substances, alcohol abuse, poor nutrition, metabolic problems, and heart failure. The liver, bile duct, and pancreas are all treated by hepatobiliary surgery. The primary cancers of the liver, such as cholangiocarcinoma, hepatocellular carcinoma, and sarcomas, are treated by the hepatobiliary surgeon. The most common cause of gallstones and their complications—cholecystitis and bile duct obstruction—appears to be a genetically determined metabolic trait causing some people to secrete lithogenic bile.
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